1. Facial tissues were originally invented to wipe off makeup. When Kleenex was introduced in 1924, it wasn't sold for runny noses! It was advertised as a disposable paper sheet for Hollywood actresses and everyday people to wipe off cold cream and makeup without ruining their cloth towels.

2. People wrote letters to companies to change the tissue's purpose. By 1930, thousands of customers wrote letters to tissue manufacturers saying they weren't using the sheets for makeup—they were blowing their noses into them! The company changed its advertising slogan to "Don't Put a Cold in Your Pocket," and sales doubled instantly.

3. Tissues are made from tiny wood fibers called cellulose. Tissues start out as natural wood chips from pine or spruce trees! The wood is boiled in water and chemicals to separate out pure cellulose fibers, which are then flattened into giant, thin paper sheets.

4. Tissues pop out of the box using an interlocking fold. Ever wonder why pulling one tissue out of the box automatically pulls the edge of the next tissue up? The sheets are folded together in an interleaved z-fold pattern, so pulling the top sheet lifts the folded corner of the sheet beneath it!

5. Multi-ply tissues are glued together with water. "2-ply" or "3-ply" tissues are made by layering two or three razor-thin paper sheets together. The layers are held together by light mechanical pressure and tiny dots of water-based adhesive, creating air pockets that make the tissue feel fluffier!

6. Colored and scented tissues used to be super popular. In the 1950s and 1960s, manufacturers sold bright pink, turquoise, yellow, and green tissues to match bathroom tile colors! However, companies mostly stopped making colored tissues because customers preferred plain white sheets made without extra dyes.

7. Your body has a completely different kind of "tissue." In biology, the word tissue means something totally different! Inside your body, groups of similar cells that work together to perform a specific job—like your muscles, heart, or brain—are also called biological tissues.